EVOLUTIONARY HISTORY OF THE VERTEBRATE PIWI GENE FAMILY

Evolutionary history of the vertebrate Piwi gene family

PIWIs are regulatory proteins that belong to the Argonaute family.Piwis are primarily expressed in gonads and protect the germline against the mobilization and propagation of transposable elements (TEs) through transcriptional gene silencing.Vertebrate genomes encode up to four Piwi genes: Piwil1, Piwil2, Piwil3 and Piwil4, but their duplication hi

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Integration of Convolutional Neural Networks and Object-Based Post-Classification Refinement for Land Use and Land Cover Mapping with Optical and SAR Data

Object-based image analysis (OBIA) has been widely used for land use and land cover (LULC) mapping using optical and synthetic aperture radar (SAR) images because it can utilize spatial information, reduce the effect of salt and pepper, and delineate LULC boundaries.With recent advances in machine learning, convolutional neural networks (CNNs) have

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Multiple interferon stimulated genes synergize with the zinc finger antiviral protein to mediate anti-alphavirus activity.

The zinc finger antiviral protein (ZAP) is a host factor that mediates inhibition of viruses in the Filoviridae, Retroviridae and Togaviridae families.We previously demonstrated that ZAP blocks replication of Sindbis virus (SINV), the prototype Alphavirus in the Togaviridae family at an early step prior to translation of the incoming genome and tha

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